CLINICAL CASE OF MECONIUM PERITONITIS AGAINST THE BACKGROUND OF CYSTIC FIBROSIS
Elena A Tkachuk,
Daria M Barykova,
Nina N Kuznetsova,
Galina P Bogonosova,
Ninel V Fomicheva,
Alexandra R Dorzhieva https://doi.org/10.57256/2949-0715-2024-2-54-60
Abstract
Relevance. Severe complications that cystic fibrosis causes require comprehensive study and prevention. Consideration of rare clinical variants of the disease is an important task for understanding the clinical manifestations of cystic fibrosis.
Aim. To present a clinical case of congenital meconium peritonitis, small intestinal volvulus and necrosis of meconium pseudocyst of the abdominal cavity, which developed against the background of cystic fibrosis.
Results. A clinical case of cystic fibrosis was considered, the cause of which was a combination of pathogenic mutations in the CFTR gene (mutation delta F508; p.Phe508 and CFTRdele2,3). Against this background, a meconium pseudocyst, meconium peritonitis and volvulus of the small intestine were formed.
Conclusion. Doctors need to be wary of hereditary pathology if patients have congenital malformations.
About the Authors
Elena A Tkachuk
FSBEI HE IGMU MINISTRY OF HEALTH OF Russia
Russian Federation
Russian Federation
Dr. Sci. (Med.), Associate Professor, Professor of the Department of Pathological Physiology and Clinical Laboratory Diagnostics, Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1; senior researcher at the «Scientific Center for Problems of Family Health and Human Reproduction», Russia, 664003, Irkutsk, st. Timiryazeva, 16; leading researcher at the «East Siberian Institute of Medical and Environmental Research», Russia, 665826, Angarsk, microdistrict 12a, building 3
Daria M Barykova
Irkutsk Order of the Badge of Honor Regional Clinical Hospital», City Ivano-Matreninskaya Children's Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57
Russian Federation
Russian Federation
geneticist «Irkutsk Order of the Badge of Honor Regional Clinical Hospital», Russia, 664049, Irkutsk, microdistrict. Yubileiny, 100; Geneticist, «City Ivano-Matreninskaya Children's Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57
Nina N Kuznetsova
City Ivano-Matreninskaya Children’s Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57
neonatologist, «City Ivano-Matreninskaya Children’s Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57
Galina P Bogonosova
City Ivano-Matreninskaya Children’s Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57; Scientific Center for Problems of Family Health and Human Reproduction», Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1
Russian Federation
Russian Federation
neonatologist of the «City Ivano-Matreninskaya Children’s Clinical Hospital», Russia, 664009, Irkutsk, Sovetskaya, 57; postgraduate student of the «Scientific Center for Problems of Family Health and Human Reproduction», Russia, 664003, Irkutsk, st. Timiryazeva, 16; Assistant of the Department of Pediatrics and Pediatric Surgery of Additional Professional Education, Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1
Ninel V Fomicheva
Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1.
Russian Federation
Russian Federation
6th year student of the Faculty of Medicine, Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1. ORCID: 0009-0008-8778-6750
Alexandra R Dorzhieva
Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1.
Russian Federation
Russian Federation
6th year student of the Faculty of Medicine, Irkutsk State Medical University, Russia, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1.
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Review
For citations:
Tkachuk E.A., Barykova D.M., Kuznetsova N.N., Bogonosova G.P., Fomicheva N.V., Dorzhieva A.R. CLINICAL CASE OF MECONIUM PERITONITIS AGAINST THE BACKGROUND OF CYSTIC FIBROSIS. Baikal Medical Journal. 2024;3(2):54-60. (In Russ.) https://doi.org/10.57256/2949-0715-2024-2-54-60
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