ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN
https://doi.org/10.57256/2949-0715-2023-2-37-44
Abstract
A study of the etiological structure of chronic viral hepatitis is presented, taking into account the assessment of the stage of the pathological process and the genotypic affiliation of pathogens in the Khorezm region of the Republic of Uzbekistan. It is shown that in the Khorezm region of Uzbekistan in the etiological structure of chronic viral hepatitis are presented as monoinfection in 42.3% of cases, in 70.7% of cases in association with other forms, including chronic hepatitis C in the form of monoinfection is 29.3 %, and in association with other forms 42.4%. The frequency of chronic hepatitis D is 15.3%. The phenomena of fibrosis are observed in 95.8% of patients with chronic viral hepatitis and are aggravated by the association of various forms of chronic viral hepatitis. The dominant genotype is genotype 1b of viral hepatitis C. The frequency of detection of this genotype increases with the progression of the stage of the disease. In patients with chronic viral hepatitis D, all amplified isolates belonged to the HBV genotype, and HDV isolates to genotype 1.
Conclusion. When treating and diagnosing chronic viral hepatitis, their etiological picture should be taken into account. This will more effectively solve the problems of implementing the Strategy of the World Health Organization and the Government of the Republic of Uzbekistan in relation to chronic viral hepatitis.
About the Authors
Shavkat R. Yusupov
Tashkent Medical Academy, Urgench branch
Uzbekistan
Uzbekistan
Kurban A. Aitov
Irkutsk State Medical University
Russian Federation
Russian Federation
Evgeny D. Savilov
Research Center for Family Health and Human Reproduction
Russian Federation
Russian Federation
Dilfuza K. Abdullayeva
Tashkent Medical Academy, Urgench branch
Uzbekistan
Uzbekistan
Safar E. Umirov
Tashkent Medical Academy, Urgench branch
Uzbekistan
Uzbekistan
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Review
For citations:
Yusupov Sh.R., Aitov K.A., Savilov E.D., Abdullayeva D.K., Umirov S.E. ETIOLOGICAL CHARACTERISTICS OF CHRONIC VIRAL HEPATITIS IN THE KHOREZM REGION OF UZBEKISTAN. Baikal Medical Journal. 2023;2(2):37-44. (In Russ.) https://doi.org/10.57256/2949-0715-2023-2-37-44
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