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GENOME EDITING (LECTURE)

https://doi.org/10.57256/2949-0715-2025-4-1-84-97

Abstract

Background. Hereditary pathology has a large proportion of morbidity in modern humans. Therefore, the search for methods for treating hereditary pathology is a particularly urgent problem. Currently, there are theoretical foundations and practical solutions for the development of methods for the etiological treatment of hereditary pathology. In this regard, genome editing methods are the most promising methods for treating hereditary pathology.

The lecture discusses the historical aspects of the development of scientific thought in the field of genome editing, technological systems, protocols and stages of developing treatments for hereditary pathology using genome editing.

Conclusion. Genome editing is one of the most promising methods for treating hereditary pathology, so doctors' awareness of this issue will allow them to use the developments of molecular biology in the future to treat human genetic diseases.

About the Authors

Elena A. Tkachuk
Irkutsk State Medical University; Scientific Center for Family Health and Human Reproduction Problems; East Siberian Institute of Medical and Environmental Research
Russian Federation


Igor Zh. Seminsky
Irkutsk State Medical University
Russian Federation


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Review

For citations:


Tkachuk E.A., Seminsky I.Zh. GENOME EDITING (LECTURE). Baikal Medical Journal. 2025;4(1):84-97. (In Russ.) https://doi.org/10.57256/2949-0715-2025-4-1-84-97

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ISSN 2949-0715 (Online)

Irkutsk State Medical University

Irkutsk Scientific Center for Surgery and Traumatology