FEATURES OF DIAGNOSIS AND MANAGEMENT OF A PATIENT WITH FREDERICK’S SYNDROME (CLINICAL OBSERVATION)
https://doi.org/10.57256/2949-0715-2024-1-53-61
Abstract
Description of a clinical case. The article presents a clinical observation of a 77-year-old patient with newly diag-nosed Frederick’s syndrome, which is a combination of a permanent form of atrial fibrillation and complete atrioven-tricular block. An exacerbation of chronic pancreatitis was the reason for hospitalization of the patient. The patient had no complaints of bradycardia or syncope, but treatment of the underlying disease was difficult due to the development of acute kidney injury against the background of chronic kidney disease and uncompensated chronic heart failure.
The cause of the development of Frederick’s syndrome was pronounced myocardium remodeling due to diseases that make up the classic complex of metabolic syndrome – coronary heart disease, arterial hypertension, type 2 dia-betes mellitus and obesity.
Conclusion. The analysis of a few domestic and foreign literature sources showed that the development of Frederick’s syndrome is associated with a worsening prognosis and the development of various complications, which is usually underestimated by attending physicians. Taking into account the difficulties of diagnosis and management of patients with this pathology, it is necessary to be wary of the development of Frederick’s syndrome, especially in comorbid elderly and senile patients. Timely medical correction and referral of the patient for surgical treatment will improve the prognosis and reduce mortality in patients with atrial fibrillation.
About the Authors
Tatiana Vladimirovna Goma
Irkutsk State Medical University, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1
Russian Federation
Russian Federation
PhD (Med.), assistant professor of the Department of Faculty Therapy
Anna Valerievna Brazis
Irkutsk State Medical University, 664003, Irkutsk, st. Krasnogo Vosstaniya, 1
Russian Federation
Russian Federation
PhD (Med.), assistant professor of the Department of Faculty Therapy
References
1. Nattel S, Allessie M, Haissaguerre M. Spotlight on atrial fibrillation-the 'complete arrhythmia'. Cardiovasc Res. 2002;54(2):197-203. DOI:10.1016/s0008-6363(02)00324-3.
2. Трекина Н.Е., Руденко А.В., Урванцева И.А. и др. Нормо-брадисистолическая форма фибрилляции предсердий (синдром Фредерика): поздняя диагностика и лечение. Клиницист. 2014;8(1):58-62 [Trekina N.Y., Rudenko A.V., Urvantseva I.A. et al. A normal bradysystolic form of atrial fibrillation (Fredericq’s syndrome): late diagnosis and treatment. 2014;8(1):58-62 (In Russian)]. DOI:10.17650/1818-8338-2014-1-58-62
3. Беннет Д.Х. Сердечные аритмии. М.: ГЭОТАР-Медиа; 2010 [Bennett D.H. Cardiac arrhythmias. M.: GEOTAR-Media; 2010 (In Russian)].
4. Кушаковский М.С. Аритмии сердца. СПб.:Фолиант; 2007 [Kushakovsky M.S. Cardiac arrhythmias. SPb.:Foliant; 2007 (In Russian)].
5. Biryukov A., Zaslavskaya E., Smirnov K. et al. TCTAP C-019 The Clinical History of a 88 Year-old Female with Acute Coronary Syndrome with ST Elevation and Frederick’s Syndrome. J Am Coll Cardiol. 2017;Apr 69 (16_Supplement):S108–S109. DOI:10.1016/j.jacc.2017.03.240
6. Шехян Г.Г., Ялымов А.А., Щикота А.М. и др. Клиническая задача по теме: «Дифференциальная диагностика и лечение нарушений сердечного ритма и проводимости сердца (ЭКС + синдром Фредерика)». РМЖ. 2016;(9):594–598 [Shekhyan G.G., Yalymov A.A., Shchikota A.M. et al. Differential diagnosis and treatment of heart rhythm and conduction disorders (clinical case). RMJ. Cardiology. 2016;(9):594–598 (In Russian)]. https://www.rmj.ru/articles/kardiologiya/Differencialynaya_diagnostika_i_lechenie_narusheniyserdechnogo_ritma_i_provodimosti_serdcaEKS__sindrom_Frederika/ [дата доступа: 30.01.2024].
7. Tzur I, Izhakian S, Gorelik O. Frederick’s syndrome: A forgotten eponym. Open J Clin Med Case Rep. 2019;5:1-3. http://jclinmedcasereports.com/articles/OJCMCR-1603.pdf [accessed: 30.01.2024].
8. Хорькова Н.Ю., Гизатулина Т.П., Колунин Г.В., Белокурова А.В. Тромбоз ушка левого предсердия у пациента с синдромом Фредерика: клиническое наблюдение. Вестник аритмологии. 2022;29(3):48-53 [Khorkova N.Yu., Gizatulina T.P., Kolunin G.V., Belokurova A.V. Left atrial appendage thrombosis and Frederick’s syndrome: a case report. Journal of Arrhythmology. 2022;29(3):48-53 (In Russian)]. DOI:10.35336/VA-2022-3-07
9. Glikson M., Nielsen J.C., Kronborg M.B. et al. ESC Scientific Document Group. 2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Eur Heart J. 2021;42(35):3427-3520. DOI:10.1093/ eurheartj/ehab364.
10. Аракелян М.Г., Бокерия Л.А., Васильева Е.Ю. и др. Фибрилляция и трепетание предсердий. Клинические рекомендации 2020. Российский кардиологический журнал. 2021;26(7):4594 [Arakelyan M.G., Bockeria L.A., Vasilieva E.Yu. et al. 2020 Clinical guidelines for Atrial fibrillation and atrial flutter. Russian Journal of Cardiology. 2021;26(7):4594. (In Russian)]. DOI:10.15829/1560-4071-2021-4594
11. Шохин А.М. Cиндром Фредерика. Материалы научно-практической конференции студентов, ординаторов и молодых ученых «Внутренние болезни на догоспитальном этапе. Эпонимы в современной практике врача». М.:ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России; 2021:42-46 [Shokhin A.M. Frederick's syndrome. Materials of the scientific and practical conference of students, residents and young scientists «Internal diseases at the prehospital stage. Eponyms in modern medical practice». M.:Russian National Research Medical University named after. N.I. Pirogov; 2021:42-46 (In Russian)]. https://rsmu.ru/fileadmin/templates/DOC/Conferences/Vnutrennie_bolezni_na_dogosp_etape/2021-eponims.pdf [дата доступа: 30.01.2024].
Review
For citations:
Goma T.V., Brazis A.V. FEATURES OF DIAGNOSIS AND MANAGEMENT OF A PATIENT WITH FREDERICK’S SYNDROME (CLINICAL OBSERVATION). Baikal Medical Journal. 2024;3(1):53-61. (In Russ.) https://doi.org/10.57256/2949-0715-2024-1-53-61
Views:
5128
